Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation
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چکیده
منابع مشابه
Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation.
The large extracellular polysaccharide Hyaluronan (HA) and its synthesizing enzymes (Has) have been implicated in regulating the migratory potential of metastatic cancer cells. Here, we analyze the roles of zebrafish Has2 in normal development. Antisense morpholino oligonucleotide (MO)-mediated knockdown of zebrafish Has2 leads to the loss of HA, and severe migratory defects during gastrulation...
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ژورنال
عنوان ژورنال: Development
سال: 2004
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.00954